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Hirose Group

member
Associate Professor HIROSE, Takashi

Research Subjects

  • Synergy of Theory and Synthesis: Rational Design and Realization of Functional Molecules
  • Chiroptical Properties from Unique Structures: Creation of Chiral π-Conjugated Systems
  • Emergent Functions via Assembly: Construction of Hierarchical Supramolecular Architectures
  • Science of Field-Responsive Materials: Functional Design via Light, Electric Fields, and Mechanical Properties

Inspired by the fundamental structures of life—helices and chirality—we are dedicated to creating innovative materials that drive next-generation optoelectronic functions.

Our group engages in the design of multifunctional materials centered on unique helical π-conjugated molecules by synergizing computational chemistry and precision organic synthesis. Specifically, we deeply explore the critical correlations between molecular structure and physical properties. Our research highlights include the development of molecular wires featuring remarkably narrow HOMO–LUMO gaps derived from distinct electronic structures, and chiral materials that exhibit highly selective responses to circularly polarized light.

Furthermore, we extend our exploration to mechanical and magnetic functionalities. This includes "molecular springs" that exhibit non-linear mechanical responses to stress, and the realization of spin-selective charge transport via the construction of hierarchical supramolecular architectures. With the goal of "tailoring molecules at will to unlock their full functional potential," we control materials from single molecules to organized structures. We aim to pioneer a new era of molecular science, with chirality and field-responsiveness as the key drivers.

Featuring a polyene-like internal structure, this π-extended helix exhibits a remarkably narrow HOMO–LUMO gap and near-infrared response. It holds great potential as a conductive chiral molecular wire. [Nat. Commun. 2022, 13, 1475.]
Face-to-face stacked chiral columnar structures consisting of helical molecules designed by terminal modification. Controlling intermolecular interactions switches the charge carriers (electron/hole), demonstrating selective transport properties along the helical axis. [J. Am. Chem. Soc. 2025, 147, 25978.]

Publications and Research Highlights