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Active dynamics of chromosome kicked by enzymatic force-dipoles

日程 : 2019年4月23日(火) 4:00 pm - 5:00 pm 場所 : 物性研究所本館6階 第5セミナー室 (A615) 講師 : 坂上貴洋 所属 : 青山学院大学 世話人 : 野口博司 (63265)
e-mail: noguchi@issp.u-tokyo.ac.jp

Inspired by recent experiments on chromosomal dynamics, we introduce an exactly solvable model for the interaction between a flexible polymer and a set of motor-like enzymes. The enzymes can bind and unbind to specific sites of the polymer and produce a dipolar force on two neighboring monomers when bound. We study the resulting nonequilibrium dynamics of the polymer and find that the motion of the monomers has several properties that were observed experimentally for chromosomal loci: a subdiffusive mean-square displacement and the appearance of regions of correlated motion. We also determine the velocity autocorrelation of the monomers and find that the underlying stochastic process is not fractional Brownian motion.

Reference:
S. Put, T. Sakaue, and C. Vanderzande, Phys. Rev. E 99, 032421 (2019).


(公開日: 2019年04月10日)